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Nov '0728

Stems Cells Not Interchangeable

by Kristine DaynesResearch

Summary: Adult stem cells produced in the brain make only specialized kinds of connections and do not adapt to other functions. For instance, a neural stem cell originating in the brain cannot replace damaged cells in the spinal cord.

Comment: This new study raises questions about other research investigating whether adult brain stems cells can replace neurons damaged by Alzheimer's, Parkinson's, multiple sclerosis, or spinal cord injuries.

Nov '078

New Discovery Tracks Brain Stem Cells

by Kristine DaynesResearch

Summary: Researchers have identified a new markets making it possible to track brain stem cells for the first time.

Comment: The discovery will open research into neurological diseases including Parkinson's disease and multiple sclerosis.

Nov '077

Neuroimmunology Gives Hopes for PD

by Kristine DaynesResearch

Summary: Recent studies have helped explain how the immune systems affects neural connections and nerve cells.

Comment: The findings are important in understanding conditions such as Parkinson's and Alzheimer's disease.

Oct '0724

Nicotine May Reduce Dyskinesias

by Kristine DaynesResearch

Summary: Research suggests that intermittent nicotine treatment may reduce medication-induced dyskinesias. Smokers are 50% less likely to develop Parkinson's disease than the general population.

Comment: Dyskinesias is sometimes a side effect of long-term levodopa therapy and has few therapy options itself.

Oct '078

Relatives of Parkinson's Patients at Risk for Dementia

by Kristine DaynesResearch

Summary: Relatives of patients with Parkinson's disease are more likely than others to develop symptoms of dementia. Researchers propose the presence of shared risk factors.

Comment: Further research will be required to identify whether the shared risk factors are genetic or related to a shared lifestyle.

Oct '078

Levodopa and Pain Threshold in PD Patients

by Kristine DaynesResearch

Summary: People with Parkinson's disease (PD) have a lower pain threshold than their peers. However, in a clinical study, levodopa increased the pain threshold of subjects with PD compared with healthy subjects who receive the same dose.

Comment: The findings confirm that patients with PD have an abnormal pain threshold.

Oct '075

Two Enzymes Protect Mitochondria, Prevent PD

by Kristine DaynesResearch

Summary: Two cell enzymes cooperate to prevent a break-down of mitochondria which could otherwise lead to Parkinson's disease.

Comment: This new understanding will help scientists develop targeted therapies for Parkinson's disease.

Oct '072

Parkinson's, Alzheimer's Have Distinctly Different Dementia

by Kristine DaynesResearch

Summary: Dementia is patients with Parkinson's disease is distinctly different from symptoms in patients with Alzheimer's. Parkinson's patients tend to have poor attention, while Alzheimer's patients have worse memory.

Comment: The different cognitive profiles between AD and PD patients suggest the diseases are caused by different pathologies.

Sep '0727

Computer Model Simulates Balance

by Kristine DaynesResearch

Summary: Scientists at Emory University have developed a computer model that simulates how the nervous system communicates with muscles to move muscles and control balance.

Comment: The findings may eventually help diagnose and treat balance problems associated with Parkinson's disease and multiple sclerosis.

Sep '0718

Gene Mutation Linked to Onset Before Age 50

by Kristine DaynesResearch

Summary: Mutations in the glucocerebrosidase (GBA) gene nearly triple the likelihood of developing Parkinson's disease and double the risk of onset before age 50.

Comment: Mutations in the GBA gene also cause Gaucher's disease, a rare disorder.

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