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Jul '0822

Blood Cell Genetics and Parkinson's Disease

by Kristine DaynesResearch

Summary: A collaboration between neurologists and a pharmocologist has led to interesting connections between blood-related genetic mechanisms and Parkinson's disease. It has been discovered that genetic mechanisms at play in blood cells also control a gene and protein that cause Parkinson's disease. Patients with Parkinson's disease were shown to have elevated levels of the alpha-synuclein protein in their brain. Clumping of this protein causes the death of neurons and produces the brain chemical dopamine.

Comment: The discovery of this link and the data and new knowledge collected from this study has given scientists a molecular switch that may trigger Parkinson's disease.

Read article - Science Daily. July 22, 2008.

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